Hi sp4c3 you can calibrate the humidity sensors with a jar and some salt. Search for hygrometer calibration and you should find info on how to do it. I haven't tried it myself. I want to now I have a bunch of sensors myself. Most read similar numbers to each other, but every so often they go out of sync further than seems correct. It can do with the placement inside your grow space, depending on how much air circulation you have.
I haven't found out about temperature calibration yet. Maybe one could use boiling water as a reference point, assuming you are at sea level. Unlike the hygrometer, I don't know how you can have a reference heat. Perhaps others have better idea.
Like VinDeezle said, I am a bit the same. I read them all, and assume between them all I've got a ball park reading. Given the grow environment is usually subject to additional forces to alter the environment, it is always in flux and thus not stable. Not unless corrected via means such as fans, heaters and humidifiers. I would be worried about leaving it to an automated system without taking the time to work out your baseline reference and such. I am working on this with my growing wardrobe.